1. Signaling Pathways
  2. Apoptosis
  3. RIP kinase
  4. RIP kinase Inhibitors

RIP kinase Inhibitors

RIPK1

RIPK2

RIPK3

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Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.

RIP kinase Inhibitors, Activators, Modulators & Degraders
Product Name RIPK1 RIPK2 RIPK3 Purity
GSK-872    
RIPK3
99.91%
Necrostatin 2 racemate
RIPK1
    99.57%
GSK-872 hydrochloride    
RIPK3
98.85%
GLPG3312  
RIPK2, IC50: 19.7 nM
  98.63%
Apostatin-1
RIPK1
    99.64%
ICCB-19 hydrochloride
RIPK1
    99.25%
UH15-38    
RIPK3, IC50: 20 nM
99.80%
GSK840    
RIPK3
99.95%
WEHI-345  
RIPK2
  99.29%
GSK-843    
RIPK3
99.53%
Necrostatin 2
RIPK1
    99.78%
GSK2983559  
RIPK2
  99.49%
PROTAC RIPK degrader-2  
RIPK2
  99.89%
RIPK-IN-4  
RIPK2, IC50: 3 nM
  99.57%
Eclitasertib
RIPK1
    99.80%
Oditrasertib
RIPK1
    99.02%
GSK2983559 active metabolite  
RIPK2
  98.86%
Aurantiamide    
RIPK3
99.56%
Ligustroflavone
RIPK1
 
RIPK3
99.90%
Necrostatin-5
RIPK1
    99.40%
RIPK3-IN-1    
RIPK3, IC50: 9.1 nM
99.30%
Ocadusertib
RIPK1
    99.57%
PK68
RIPK1, IC50: 90 nM
RIPK1, EC50: 23 nM
    99.92%
OD36  
RIPK2, IC50: 5.3 nM
  99.33%
LD4172
hRIP1, Ki: 4.8 nM
    98.32%
RIPK1-IN-4
RIPK1
    98.89%
Zharp1-211
RIPK1, EC50: 53 nM
RIPK1, Kd: 8.7 nM
    99.15%
cRIPGBM chloride  
RIPK2
  99.82%
HTH-01-091  
RIPK2
  99.81%
ZB-R-55
RIPK1, IC50: 5.7 nM
    99.39%
Flizasertib
hRIP1, Ki app: 0.00071 μM
    99.9%
RIPK1-IN-17
RIPK1, Kd: 17 nM
   
GSK2983559 free acid  
RIPK2
  99.49%
NecroIr1
RIPK1
 
RIPK3
98.53%
RIPK1-IN-19
RIPK1, IC50: 15 nM
    98.87%
KBU2046
RIPK1
    99.52%
KWCN-41
RIPK1, IC50: 88 nM
    99.83%
SZM679
RIPK1, Kd: 8.6 nM
 
RIPK3, Kd: >5000 nM
99.59%
NecroIr2
RIPK1
 
RIPK3
98.02%
Necrostatin-34
RIPK1
    98.90%
WEHI-345 analog  
RIPK2
  98.41%
PROTAC RIPK1 Degrader-1
RIPK1
   
OD36 hydrochloride  
RIPK2, IC50: 5.3 nM
 
cRIPGBM  
RIPK2
 
RIP1-IN-1
RIPK1, Kd: 110 nM
   
RIPK1-IN-25
RIPK1, EC50: 19.9 nM
RIPK1, Kd: 25 nM
   
RIPK2/3-IN-2  
RIPK2, IC50: 16 nM
RIPK3, IC50: 18 nM
99.67%
Zharp1-163
RIPK1, Kd: 240 nM
RIPK1, IC50: 406.1 nM
   
RIPK1-IN-34
RIPK1, IC50: 126.7 nM
   
RIPK1-IN-37
RIPK1
   
Tat-ASIC1a (1-20) (mouse, rat)
RIPK1
   
RIPK1-IN-18
RIPK1
   
RIPK1/RIPK3-PPI-IN-1
RIPK1, Kd: 2.4 nM
 
RIPK3, Kd: 24 nM
VWK147
RIPK1
   
RIPK1-IN-38
RIPK1, IC50: 27 nM
   
RIPK1-IN-11
RIPK1
   
PB830
hRIP1, IC50: <100 nM μM
   
RIPK1-ligand-2
RIPK1
   
RIPK1-IN-14
RIPK1
   
NOD1-RIPK2-IN-1  
RIPK2, IC50: 1.52 nM
 
SZM-1209
RIPK1, Kd: 85 nM
 
RIPK3, Kd: >10000 nM
RIPK3-IN-6    
RIPK3
98.03%
RIPK1-IN-22
RIPK1
   
RIPK1-IN-36
RIPK1, EC50: <25 nM
   
RIPK1-IN-31
hRIP1, IC50: 16 nM
   
NDs-IN-1
RIPK1
   
Necroptosis inducer 2    
RIPK3
RIPK2-IN-8  
RIPK2, IC50: 11 nM
RIPK3, IC50: 44.61 nM
RIPK1-IN-41
RIPK1, IC50: 92 nM
RIPK1, Kd: 106.8 nM
   
IL-6/RIPK3-IN-1    
RIPK3, IC50: 1.32 μM
RIPK1-IN-40
RIPK1
   
Necrostatin-21
RIPK1
   
CSLP43  
RIPK2, IC50: 19.9 nM
 
RIPK1-IN-39
RIPK1, IC50: 69.40 nM
 
RIPK3, IC50: 6946 nM
WJH-C19
RIPK1, IC50: 5.7 nM
    98.65%
RIPK1-IN-29
RIPK1, IC50: 6.9 nM
   
RIPK2-IN-2  
RIPK2
 
RIPK1-IN-23
RIPK1
   
RIPK2-IN-7  
RIPK2, IC50: 0.6 nM
 
Nec-3a
RIPK1, IC50: 0.44 μM
   
RIP1 kinase inhibitor 4
RIPK1, EC50: ≤ 1000 nM nM
   
RIP2 Kinase Inhibitor 4  
RIPK2, pIC50: 8
 
CSLP37  
RIPK2, IC50: 16.3 nM
 
Necroptosis-IN-5
RIPK1
   
RIPK1-IN-8
RIPK1
   
RIPK1-IN-35
RIPK1, IC50: 5.33 nM
   
RIPK1-IN-32
RIPK1
   
Ligustroflavone (Standard)
RIPK1
 
RIPK3
RIPK1 ligand-Linker Conjugate-1
RIPK1